Endocrine Abstracts

Causing production of free radicals and reduction of antioxidant system activity, in the pancreatic β-cells, in particular, resulting in reduction in insulin production and consequently to hyperglycemia, oxidative stress could be a pathogenetic mechanism of morbidity in diabetes mellitus. Search for and development of medicines with antioxidant and hypoglycemic activity remains urgent.Aim: The work was initiated to study antioxidant and hypoglycemic...